INTESTINAL MICROBIOTA IN NEWBORNS WITH ALLERGIC REACTIONS

Abstract

The composition of the microbiota of an infant with atopy has some features even before the development of allergy in a newborn. The results of clinical and microbiological examination of 46 newborns with a history of maternal allergy were studied. 26 boys and 20 girls who were admitted to the neonatology department were examined. A study of the anamnesis of newborn mothers showed that 33-71.7% had food allergies, 8-17.4% had urticaria and 5-10.9% had Quincke's edema. The cause of allergies in mothers were more often honey (10-21.7%), sweets and chocolate (9-19.6%), eggs (5-10,9%). 25-54,3% women received antibiotics during pregnancy due to exacerbation of chronic diseases and complicated course of labor. Operative delivery was noted in 7-15.2% of mothers, bacterial vaginosis – in 11-23.9% of cases. The study of the composition of the intestinal microbiota showed noticeable changes, both qualitatively and quantitatively. Upon admission to the hospital, the intestinal flora in newborns was poor: both the detection frequency and the quantitative content of normal intestinal inhabitants were sharply reduced: bifidobacteria were detected in the 6th dilution in 35-76.1% of patients, enzymatically defective escherichia were sown in 27-58.6% of cases and non-hemolytic enterococci were isolated – only in 18-39.1% babies.